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Anti-Inflammatory Data Analysis
The two plots above depict the probability of anti-inflammatory property and isoelectric point at a pH of 1.3 and a pH of greater than 2. Having high confidence of the anti-inflammatory property, values greater or equal to 0.468, are colored green. Having medium confidence, values less than 0.468 and greater than or equal to 0.388, are colored yellow. Having low confidence, values less than 0.388 and less than or equal to 0.342, are colored red. Based on the plots, all the high and medium sequences vary between isoelectric points from 2 to 14 for both pH environments. Based on the results, we can conclude there is no correlation between anti-inflammatory properties and isoelectric point.
These two plots above depict the probability of anti-inflammatory property and total net charge at a pH of 1.3 and a pH of greater than 2. Based on the plots, all the high and medium confidence anti-inflammatory properties vary in both positive and negative net charge. Based on these results, we can conclude there is no correlation between anti-inflammatory properties and total net charge.
These plots show the probability of antimicrobial properties plotted against the hydrophobicity percentage for both pepsin of pH 1.3 and pepsin of pH>2. From this chart, there is not much of a trend, so it does not seem to correlate between the antimicrobial properties and the hydrophobicity of peptide sequences.
These plots show the anti-inflammatory probability of a peptide plotted against the percentage of helix in the structure of the peptide. Peptides cut using pepsin of pH 1.3 and a pH > 2 are both represented. Neither plot seems to show any correlation between the anti-inflammatory properties and the helix structure so the conclusion can be drawn that there is no correlation.
These plots show the anti-inflammatory probability of a peptide plotted against the percentage of sheet in the structure of the peptide. Peptides cut using pepsin of pH 1.3 and a pH > 2 are both represented. Neither plot seems to show any correlation between the anti-inflammatory properties and the sheet structure so the conclusion can be drawn that there is no correlation.
These plots show the anti-inflammatory probability of a peptide plotted against the percentage of coil in the structure of the peptide. Peptides cut using pepsin of pH 1.3 and a pH > 2 are both represented. Neither plot seems to show any correlation between the anti-inflammatory properties and the coil structure so the conclusion can be drawn that there is no correlation.
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